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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Caffeic acid phenethyl ester, Paclitaxel
Phytochemical Name Caffeic acid phenethyl ester (PubChem CID: 5281787 )
Anticancer drug Name Paclitaxel (PubChem CID: 36314 )
Structure of
Phytochemical
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2D MOL 3D MOL
Structure of
Anticancer Drug
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2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 779
Pair Name Caffeic acid phenethyl ester, Paclitaxel
Disease Info [ICD-11: 2C73] Ovarian cancer Investigative
Biological Phenomena Inhibition-->Cell migration
In Vitro Model OV7 Ovarian carcinoma Homo sapiens (Human) CVCL_2675
Result The simultaneous administration of PTX and CAPE enhanced the anti-migration activity of the chemotherapeutic used in this study.
03. Reference
No. Title Href
1 Caffeic Acid Phenethyl Ester (CAPE) Synergistically Enhances Paclitaxel Activity in Ovarian Cancer Cells. Molecules. 2023 Aug 1;28(15):5813. doi: 10.3390/molecules28155813. Click
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